Warmuth et al., Ba/F3 cells and their use in kinase drug discovery., Curr Opin Oncol. 2007 Jan;19(1):55-60
PMID: 17133113
Cellosaurus: CVCL_0161
DSMZ: ACC 300
IL3-dependend mouse cell line derived from C3H mouse strain; the precise origin of the cell line is unclear; however, performing May-Grünwald-Giemsa staining provides evidence that the cells are indeed from a lymphatic back ground.
reverse transcriptase positive by ELISA and PCR (DSMZ)
SMRV negative by PCR (DSMZ)
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active reverse transcriptase suggests the precense of a retrovirus of unknown identity. Data concerning the identity of the retrovirus can be presented to the ZKBS for re-evaluation of the cell line
