Details zum Onkogen
| PKP3 shRNA* | |
| Nukleinsäure | |
| Suppression der Expression von PKP3 (siehe Eintrag) | |
| ohne Gefährdungspotential | |
| PKP3 is overexpressed in certain pancreatic and ovarian cancer cells [1,2]. Overexpression of PKP3 coding sequences in primary murine keratinocytes resulted in cellular transformation (anchorage-independent growth) [3]. | |
| [1] Lim, V. et al., Biochem Biophys Res Commun, 2019, 508 (2), 646–653. doi: 10.1016/j.bbrc.2018.11.163. [2] Du, Y. et al., Biomedicines, 2023, 11 (9). doi: 10.3390/biomedicines11092472. [3] Müller, L. et al., Cell Rep, 2023, 42 (1), 112031. doi: 10.1016/j.celrep.2023.112031. | |