ATCC CRL-1991:
Cells contain Epstein-Barr virus viral DNA sequences
T1 is the parental line for the T2 (174 x CEM.T2) line (ATCC CRL-1992), and together the lines are useful for studying antigen processing and T cell recognition of class I major histocompatibility antigens.
Salter RD, et al. Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. Immunogenetics 21: 235-246, 1985. PubMed: 3872841
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This line is a cloned hybrid between the 721.174 (variant of the LCL 721 B lymphoblastic cell line) and CEMR.3 (8-azaguanine and ouabain resistant clone of the CEM T lymphoblastic cell line).
Humane CD4 positive T-Zell/ B-Zell Hybridzelllinie, entstanden durch PEG-Fusion von 721.174 und CEM.3 Zellen.
