Federal office of Consumer Protection and Food safetyZKBS

Oncogene database

Welcome to the oncogene database

Here you have the opportunity to inform yourself about cellular and viral genes/nucleic acids that have been assessed in regard to their oncogenic potential by the ZKBS or its office. The hazard potential arising from a protein?s immunomodulatory, neurodegenerative or toxic properties are unrelated to its oncogenic potential and are therefore not assessed. This list is continuously expanded and updated.

Note: Entries of designated oncogenes and/or tumour suppressor genes originating before 01.01.2017 may be outdated due to changed criteria relating to the assessment of oncogenes. You are advised to contact the office of the ZKBS (e.g. via the contact form on the main page) to inquire about the status of such genes.
The following genes/nuclei acids display transforming potential:
  • genes/nuclei acids that enable the anchorage-independent growth of relevant vertebrate cell lines in vitro
  • genes/nucleic acids that induce tumours in animals.
Besides the original literature the following databases are used for the assessment:
registration dateGene/Nuc. acidfunctionclassification
7/28/23SMARCB1 shRNA Suppression der Expression von SMARCB1 (siehe Eintrag)oncogene
7/28/23SMARCB1 DNA-binding protein; Core component of the BAF (hSWI/SNF) co ...tumour suppressor
7/21/23WNT7B und shRNA Signaling protein; Ligand for members of the frizzled family ...without hazard potential
7/21/23AFM und shRNA Glycoprotein; Member of the albumin gene family, which is co ...without hazard potential
7/20/23NGFR und shRNA Neurotrophin receptor; Nerve growth factor receptor contain ...without hazard potential
7/11/23TOX und shRNA Transcriptional regulator; TOX thymocyte selection associate ...without hazard potential
7/11/23ZEB2 shRNA Suppression der Expression von ZEB2 (siehe Eintrag)without hazard potential
7/11/23ZEB2 transcriptional inhibitor, ZEB2 Zinc finger E-box-binding ho ...oncogene
6/30/23TOX2 und shRNA Putative transcriptional activator; involved in the hypothal ...without hazard potential
6/27/23FYB1 und shRNA FYN-binding protein 1, acts as an adapter protein of the FYN ...without hazard potential
6/27/23POU2F2 und shRNA transcription factor; a homeobox-containing transcription fa ...without hazard potential
6/22/23FAP und shRNA serine protease; cell surface glycoprotein serine protease t ...without hazard potential
5/10/23PAX7 and shRNA transcription factor, involved in organogenesis and tissue d ...without hazard potential
5/10/23SPATA18 und shRNA Mitochondria-eating protein, This gene encodes a p53-inducib ...without hazard potential
5/10/23CLCA2 und shRNA Calcium-activated chloride channel regulator, CLCA2 belongs ...without hazard potential
5/10/23POU2F3 und shRNA transcription factors; Member of the POU domain family of tr ...without hazard potential
5/10/23ELF3 shRNA Suppression der Expression von ELF3 (siehe Eintrag)without hazard potential
5/10/23ELF3 transcription factor; ELF3 (E74 like ETS transcription facto ...oncogene
5/9/23SOX18 and shRNA transcription factor, involved in embryonal cardiovascular t ...without hazard potential
5/8/23ONECUT3 and shRNA transcription factor with CUT domain and homeodomainwithout hazard potential
5/8/23GOT1 and shRNA cytosolic glutamate oxaloacetrate transaminase; enzyme in gl ...without hazard potential
5/3/23ZIC1 and shRNA transcription factor, involved in neurogenesiswithout hazard potential
4/26/23PROM1 und shRNA transmembrane protein; located in ER, Golgi and cell membran ...without hazard potential
3/20/23BARX2 und shRNA transcription factor; member of the homeobox transcription f ...without hazard potential
3/20/23TEAD4 shRNA Suppression der Expression von TEAD4 (siehe Eintrag)without hazard potential

Commercial use of the data is not permitted

 Assessment done by the office of the ZKBS

© Bundesamt für Verbraucherschutz und Lebensmittelsicherheit