Federal office of Consumer Protection and Food safetyZKBS

Oncogene database

welcome to the oncogene database

With this database you have the opportunity to inform yourself about cellular and viral genes/nucleic acids that have been assessed by the ZKBS or its office in regard to their oncogeneic potential. This list is continuously updated.

The oncogenic potential of genes/nucleic acids is assessed based on the following criteria:
  • genes/nucleic acids of oncogenic viruses which are shown to be responsible for the oncogenic transformation,
  • genes/nucleic acids which are shown to be essential for the development of human tumours,
  • genes/nucleic acids which are shown to be responsible for the transformation of mammalian cell cultures,
  • genes/nucleic acids which are shown to cause tumours in animal models.
The following databases as well as the original literature are used for the assessment:
registration dateGene/Nuc. acidfunctionclassification
1/30/20YTHDF3 und shRNA
Assessment done by the office of the ZKBS
regulator of mRNA translation; Specifically recognizes and b ...without hazard potential
1/30/20YTHDF1 und shRNA
Assessment done by the office of the ZKBS
regulator of mRNA translation; Specifically recognizes and b ...without hazard potential
1/30/20YTHDC1 und shRNA
Assessment done by the office of the ZKBS
Regulator of alternative splicing; specifically recognizes a ...without hazard potential
1/30/20WTAP und shRNA
Assessment done by the office of the ZKBS
Associated component of the WMM complex, a complex that medi ...without hazard potential
1/30/20WDR36 und shRNA
Assessment done by the office of the ZKBS
Involved in the nucleolar processing of SSU 18S rRNA. Involv ...without hazard potential
1/30/20VIRMA und shRNA
Assessment done by the office of the ZKBS
Associated component of the WMM complex, a complex that medi ...without hazard potential
1/30/20UTP4 und shRNA
Assessment done by the office of the ZKBS
Ribosome biogenesis factor; Involved in nucleolar processing ...without hazard potential
1/29/20U2AF2 und shRNA
Assessment done by the office of the ZKBS
RNA-binding protein; Plays a role in pre-mRNA splicing and 3 ...without hazard potential
1/29/20TOP3B und shRNA
Assessment done by the office of the ZKBS
DNA topoisomerase; Releases the supercoiling and torsional t ...without hazard potential
1/29/20TIAL1 und shRNA
Assessment done by the office of the ZKBS
RNA-binding protein; Possesses nucleolytic activity against ...without hazard potential
1/29/20SYNCRIP und shRNA
Assessment done by the office of the ZKBS
Heterogenous nuclear ribonucleoprotein; implicated in mRNA p ...without hazard potential
1/29/20SART3 und shRNA
Assessment done by the office of the ZKBS
snRNP-binding protein; functions as a recycling factor of th ...without hazard potential
1/29/20SAFB2 und shRNA
Assessment done by the office of the ZKBS
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can ...without hazard potential
1/29/20RPUSD4 und shRNA
Assessment done by the office of the ZKBS
mRNA pseudouridine synthase; Catalyzes uridine to pseudourid ...without hazard potential
1/29/20RPUSD3 und shRNA
Assessment done by the office of the ZKBS
mRNA pseudouridine synthase; Catalyzes uridine to pseudourid ...without hazard potential
1/29/20RBM28 und shRNA
Assessment done by the office of the ZKBS
The protein encoded by this gene is a specific nucleolar com ...without hazard potential
1/29/20RBM3 shRNA
Assessment done by the office of the ZKBS
Suppression der Expression von RBM3 (siehe Eintrag)without hazard potential
1/29/20RBM3
Assessment done by the office of the ZKBS
mRNA binding protein; enhances global protein synthesis at b ...oncogene
1/29/20RALY und shRNA
Assessment done by the office of the ZKBS
RNA-binding protein; acts as a transcriptional cofactor for ...without hazard potential
1/29/20QKI und shRNA
Assessment done by the office of the ZKBS
RNA-binding protein; regulates pre-mRNA splicing, export of ...without hazard potential
1/29/20PUS7L und shRNA
Assessment done by the office of the ZKBS
Pseudouridylate synthase; catalyzes pseudouridylation of RNA ...without hazard potential
1/29/20PUS7 und shRNA
Assessment done by the office of the ZKBS
Pseudouridylate synthase; catalyzes pseudouridylation of RNA ...without hazard potential
1/29/20PUF60 und shRNA
Assessment done by the office of the ZKBS
DNA- and RNA-binding protein; involved in several nuclear pr ...without hazard potential
1/29/20PRPF31 und shRNA
Assessment done by the office of the ZKBS
spliceosome subunit; Involved in pre-mRNA splicingwithout hazard potential
1/29/20PPAN und shRNA
Assessment done by the office of the ZKBS
May have a role in cell growth.without hazard potential

Commercial use of the data is not permitted

 Assessment done by the office of the ZKBS


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