export protein; mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2.
ohne Gefährdungspotential
XPO1 RNA interference suppressed gastric cancer cell growth.
Die ursächliche Beteiligung an der Entstehung von Tumoren ist nicht gezeigt.
Sexton R et al., Int J Mol Sci. 2019 Sep 28;20(19).
