RNA-binding protein; acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP)
ohne Gefährdungspotential
Knockdown of RALY expression using a specific shRNA suppressed the proliferation, migration, and invasion capabilities of hepatocellular carcinoma cells in vitro.
Die ursächliche Beteiligung an der Entstehung von Tumoren ist nicht gezeigt.
Zhu Z et al., Cancer Manag Res. 2018 Nov 9;10:5559-5572.